Said El-deib
NMC Royal Hospital, UAE
Consultant pediatrician at MOHP&EMS, Egypt
Abstract
The gut microbiota plays a pivotal role in the maintenance of human health. Numerous factors, including the mode of delivery, impact early gut colonization in newborns. Recent research focuses on the use of probiotics in the prevention of gut dysbiosis in newborns delivered by cesarean section (CS)
Infants born by caesarean section or receiving antibiotics are at increased risk of developing metabolic, inflammatory and immunological diseases, potentially due to disruption of normal gut microbiota at a critical developmental time window. We are focusing on whether probiotic supplementation could ameliorate the effects of antibiotic use or caesarean birth on infant
The probiotic supplement had a strong overall impact on the microbiota composition, but the effect depended on the infant’s diet. Only breastfed infants showed the expected increase in bifidobacteria and reduction in Proteobacteria and Clostridia.
The α-diversity of the intestinal microbiota of cesarean delivery neonates was significantly lower than that of the naturally delivered neonates
The delivery mode is considered to be a significant influencing factor in the early gut microbiota composition, which is associated with the long-term health of the host. In this study, we tried to explore the effects of probiotics on the intestinal microbiota of C-section neonates
Conclusions:
The results indicate that it is possible to correct undesired changes in microbiota composition and function caused by antibiotic treatments or caesarean birth by supplementing infants with a probiotic mixture together with at least partial breastfeeding.
Biography
Dr. Said El Deib is a consultant pediatrician at MOHP&EMS Egypt Neonatologist and clinical researcher with experience in the field spans 15 years, backed by a higher education degree MRCPCH from Royal College of Pediatrics ‘and Child health in UK (London), in addition to master degree from Ain Shams university in Egypt one of the oldest and top ranking universities in the MENA region. He is pioneering an open and contextual evaluation model based on constructive responses, which has led in the creation of new methods to improve pediatric healthcare, neonatology and pediatric nutrition. Dr. said has established this model following his years of experiences in medical practice, research and evaluation, and teaching and administration in hospitals and medical universities in the reigion, including Egypt, kuwait and the UAE.
Dr. said has published studies in reputable international journals in neonatology and pediatric nutrition. He has also presented his findings in prestigious international conferences and sy